Newsbin is installed on a SSD,
In the options select "Open Data Folder". Does it open the SSD drive? The install folder and where the data files all reside is completely disconnected.
I'm wondering if you have a massive download list DB or maybe a huge signature or "downloadMarker.db3" file?
If you have nothing in the download list, you might do "open data folder" again, exit Newsbin and delete "DownloadsV2.db3". This will wipe the download, failed and wish lists.